Article

Similar, but not the same: multi-omics comparison of human valve interstitial cells and osteoblast osteogenic differentiation expanded with an estimation of data-dependent and data-independent PASEF

2024-04-04

Abstract excerpt

Osteogenic differentiation is crucial in normal bone formation and pathological calcification, such as calcific aortic valve disease (CAVD). Understanding the proteomic and transcriptomic landscapes underlying this differentiation can unveil potential therapeutic targets for CAVD. In this study, we employed the timsTOF Pro platform to explore the proteomic profiles of valve interstitial cells (VICs) and osteoblast...

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Literature Corpus work: dd8b9a96-a554-5439-8e2d-6a4a7c4f9df5
DOI: 10.1101/2024.04.03.587893

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