Article

Conserved and Divergent Modulation of Calcification in Atherosclerosis and Aortic Valve Disease by Tissue Extracellular Vesicles

2020-04-03

Abstract excerpt

<h4>Background</h4> Fewer than 50% of patients develop calcification of both atherosclerotic plaques and aortic valves, implying differential pathogenesis. While circulating extracellular vesicles (EVs) act as biomarkers of cardiovascular diseases, tissue-entrapped EVs associate with early mineralization, but their contents, function, and contributions to disease remain unknown. <h4>Results</h4> Global proteomic...

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Literature Corpus work: 8f831c04-70db-572f-94e9-7dbfac1be768
DOI: 10.1101/2020.04.02.022525

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