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Article

Proteomic analysis of interstitial aortic valve cells acquiring a pro-calcific profile.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Renato Millioni, Bertacco Elisa, Franchin Cinzia, Arrigoni Giorgio, Rattazzi Marcello

Abstract excerpt

Cell-driven processes are now considered of relevance for the pathogenesis of aortic stenosis. In particular, during calcific valve degeneration, interstitial valve cells (VIC) resident in the leaflet can acquire an osteogenic/pro-calcific profile and actively contribute to matrix mineralization. The proteomic study described in this chapter is undertaken to investigate modifications in the proteome of bovine...

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Share to Aortic Valve
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 23606251
DOI: 10.1007/978-1-62703-386-2_8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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