Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis

Abstract excerpt

<title>Abstract</title> <p>Amyotrophic lateral sclerosis (ALS) is a relentless neurodegenerative syndrome of the human motor neuron system, for which no effective treatment exists. Variability in the rate of disease progression limits the efficacy of ALS clinical trials, suggesting that developing of better biomarkers for prognosis will facilitate therapeutic progress. Here, we applied unbiased next-generation se...

Topics

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• Amyotrophic Lateral Sclerosis Research
• biodegradable polymer synthesis and properties
• Neurogenetic and Muscular Disorders Research
• Prion Diseases and Protein Misfolding
• RNA Research and Splicing

Identifiers and source

Literature Corpus work

0018a789-4151-5cdd-99a1-377cab8561ca

DOI

10.21203/rs.3.rs-554057/v1