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Article

Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis

2019-11-14

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a relentless neurodegenerative syndrome of the human motor neuron system, for which no effective treatment exists. Variability in the rate of disease progression limits the efficacy of ALS clinical trials, suggesting that developing of better biomarkers for prognosis will facilitate therapeutic progress. Here, we applied unbiased next-generation sequencing to investigate the...

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Literature Corpus work
ea661a94-bd87-524c-84f3-b9ab895b1479
DOI
10.1101/833079
Open publication

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Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosisDOI 10.1101/833079
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