Article

ALDH1-positive intratumoral stromal cells indicate epithelial differentiation and good prognosis in prostate cancer

2018-03-05

Abstract excerpt

Aldehyde dehydrogenase 1 (ALDH1) characterizes tumor-initiating cells in solid tumors, however little is known about its expression in intratumoral stromal cells. Herein, we aimed to dissect its potential dual relevance in prostate cancer (PCa). ALDH1 expression was evaluated immunohistochemically in tumor and stromal cells in primary PCa and metastasis. It was correlated with clinico-pathological parameters, outc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd6d5d44-0830-503f-83df-c68ffc03cbbc
DOI: 10.1101/276378

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ALDH1-positive intratumoral stromal cells indicate epithelial differentiation and good prognosis in prostate cancerDOI 10.1101/276378Read

The aldehyde dehydrogenase enzyme 7A1 is functionally involved in prostate cancer bone metastasisSemantic proximity Read

The distinct role of ALDH1A1 and ALDH1A3 in the regulation of prostate cancer metastasesSemantic proximity Read

Somatic aberrations of BRCA1 gene are associated with progressive and stem cell-like phenotype of prostate cancerSemantic proximity Read

Characterization and clinical relevance of ALDHbright populations in prostate cancer.Semantic proximity Read

Prolyl 4-hydroxylase subunit beta (P4HB) could serve as a prognostic and radiosensitivity biomarker for prostate cancer patientsSemantic proximity Read

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanismSemantic proximity Read

Gene Expression Profiles of Prostate Cancer Stem Cells Isolated by Aldehyde Dehydrogenase Activity AssaySemantic proximity Read

Aldehyde dehydrogenase 1 expression correlates with the invasion of breast cancer.Semantic proximity Read

The Significance of Aldehyde Dehydrogenase 1 in CancersSemantic proximity Read

ALDH1A3 serves as a predictor for castration resistance in prostate cancer patientsSemantic proximity Read

Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor CellsSemantic proximity Read

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanismSemantic proximity Read