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Article

Characterization and clinical relevance of ALDHbright populations in prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2013

Le Magnen Clémentine, Bubendorf Lukas, Rentsch Cyrill A, Mengus Chantal, Gsponer Joel, Zellweger Tobias, Rieken Malte, Thalmann George N, Cecchini Marco G, Germann Markus, Bachmann Alexander, Wyler Stephen, Heberer Michael, Spagnoli Giulio C

Abstract excerpt

PURPOSE: High aldehyde dehydrogenase (ALDH) has been suggested to selectively mark cells with high tumorigenic potential in established prostate cancer cell lines. However, the existence of cells with high ALDH activity (ALDH(bright)) in primary prostate cancer specimens has not been shown so far. We investigated the presence, phenotype, and clinical significance of ALDH(bright) populations in clinical prostate...

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Identifiers

PMID: 23969936
DOI: 10.1158/1078-0432.CCR-12-2857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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