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The Significance of Aldehyde Dehydrogenase 1 in Cancers

30 Dec 2024

Abstract excerpt

The goal of this paper is to discuss the role of ALDH isozymes in different cancers, review advances in ALDH1-targeting cancer therapies, and explore a mechanism that explains how ALDH expression becomes elevated during cancer development. ALDH is often overexpressed in cancer, and each isoform has a unique expression pattern and a distinct role in different cancers. The abnormal expression of ALDHs in different...

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PMID: 39796106
DOI: 10.3390/ijms26010251

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