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Gene Expression Profiles of Prostate Cancer Stem Cells Isolated by Aldehyde Dehydrogenase Activity Assay

16 May 2012

Abstract excerpt

PURPOSE: Prostate cancer cells include a small population of cancer stem-like/cancer initiating cells, which have roles in cancer initiation and progression. Recently aldehyde dehydrogenase activity was used to isolate stem cells of various cancer and normal cells. We evaluated the aldehyde dehydrogenase activity of the human prostate cancer cell line 22Rv1 (ATCC®) with the ALDEFLUOR® assay and determined its...

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PMID: 22608744
DOI: 10.1016/j.juro.2012.02.2555

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