Article

Improved mRNA stability and biocompatibility through self-gelatinizable nucleic acids

2025-10-21

Abstract excerpt

Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA-based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems. Lipid nanoparticles (LNPs) currently serve as the primary vehicle for mRNA delivery, with well-documented clini...

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Literature Corpus work: dd64d256-60bc-58b2-b7dc-5ede0da05941
DOI: 10.22541/au.176105542.23261403/v1

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