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Dominant Negative Mitf Allele Impacts Melanophore and Xanthophore Development and Reveals Collaborative Interactions With Tfec in Zebrafish Chromatophore Lineages.

Pigment cell & melanoma research - 1 Mar 2025

Korzeniwsky Katia G, de Mello Pietro L H, Liang Yipeng, Feltes McKenna, Farber Steven A, Parichy David M

Abstract excerpt

Ectothermic vertebrates exhibit a diverse array of pigment cell types-chromatophores-that provide valuable opportunities to uncover mechanisms of fate specification and how they evolve. Like melanocytes of mammals, the melanophores of teleosts and other ectotherms depend on basic helix-loop-helix leucine zipper transcription factors encoded by orthologues of MITF. A different chromatophore, the iridescent...

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Identifiers

PMID: 40123122
DOI: 10.1111/pcmr.70009
PMCID: PMC11931198

Genes

MITF

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