Article

Super-dosed butyrate induces a revisable metabolic paralysis through transient mitochondrial reprogramming in the gut-brain axis

2020-12-26

Abstract excerpt

<h4>Background and purpose</h4> Sodium butyrate (SB) is a major product of gut microbiota with signaling activity in the human body. However, the toxic effect of SB remains largely unknown. This issue is addressed in current study. <h4>Experimental approach</h4> SB (0.3 – 2.5 g/kg) was administrated through a single peritoneal injection in mice. The core body temperature and mitochondrial function in the brain h...

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Literature Corpus work: dd4985a8-7f6c-57c5-9a89-016d06df4b6a
DOI: 10.1101/2020.12.23.424102

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