Article

Assessment of a new class of slow γ-aminobutyric acid type A receptor anesthetic on mouse neuronal and astrocyte mitochondrial function

2025-09-11

Abstract excerpt

<title>Abstract</title> <p>Our previous work has demonstrated efficacy of a new chemical class of the slow γ-aminobutyric acid type A receptor anesthetics that produce minimal effects on breathing and hemodynamics in rats. To advance pre-clinical testing, we screened one member of our class of compounds, KSEB 14 − 01, for mitochondrial toxicity in primary neuronal and astrocyte cultures from mice. Prior to treatm...

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Literature Corpus work: f80c626b-2b17-5428-814d-5d8fab8a3f0b
DOI: 10.21203/rs.3.rs-6659152/v1

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Assessment of a new class of slow γ-aminobutyric acid type A receptor anesthetic on mouse neuronal and astrocyte mitochondrial functionDOI 10.21203/rs.3.rs-6659152/v1Read

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