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MiR-302a reprogrammed fibroblast-derived induced anti-aging neural stem cells improve cognition and prolong lifespan in Alzheimer's disease model

2023-06-05

Abstract excerpt

<h4>Background: </h4> Neural stem cells (NSC) are essential for maintaining tissue homeostasis and promoting longevity in living organisms. As a promising approach to treating neurodegenerative diseases, NSC transplantation has been hampered by crucial issues such as cellular senescence, immune rejection, and low cell viability. <h4>Methods: </h4>: MiR-302a was used to reprogram human and mouse fibroblast cells i...

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Literature Corpus work: dd25a1e2-aa5c-5c0f-a6d5-a6e5fcdc3250
DOI: 10.21203/rs.3.rs-3005271/v1

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