Article
Characterising the in vitro conversion of mouse fibroblasts into induced neurons using a CRISPR/Cas9 knock-out screen
2020-01-01
Abstract excerpt
As the global phenomenon of population aging has become very prominent in the last few decades, diseases of the aging such as Alzheimer’s and Parkinson’s disease have taken the spotlight as the new challenges of modern medicine. In fact, aging is the biggest risk factor for neurodegeneration. Neurodegenerative diseases are particularly difficult to study, as animal models often fail to recapitulate human disease p...
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Identifiers and source
- Literature Corpus work
- c414c2c2-509f-5117-8f70-6b5c7db136f8
- DOI
- 10.7488/era/282