Article

Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy

2021-05-27

Abstract excerpt

The extracellular matrix (ECM) collagen undergoes major remodeling during tumorigenesis. However, alterations to the ECM are not widely considered in cancer diagnostics, due to mostly uniform appearance of collagen fibers in white light images of hematoxylin and eosin-stained tissue sections. Polarimetric second-harmonic generation (P-SHG) microscopy enables label-free visualization and ultrastructural investigati...

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Literature Corpus work: 8fc67bff-a555-5afe-90e5-a70fd824a4c1
DOI: 10.1101/2021.05.26.445874

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