Article

Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated fibroblasts

2020-06-23

Abstract excerpt

During the last ten years, many research results have been referring to a particular type of cancer-associated fibroblasts associated with poor prognosis, invasiveness, metastasis and resistance to therapy in multiple cancer types, characterized by a gene expression signature with prominent presence of genes COL11A1 , THBS2 and INHBA . Identifying the underlying biological mechanisms responsible for their creat...

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Literature Corpus work: dd0b6c87-799b-59ea-992f-0eaca3f28687
DOI: 10.1101/2020.06.23.166066

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