Article

Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis

2024-03-07

Abstract excerpt

<h4>Summary</h4> Obesity is a predisposition factor for breast cancer, suggesting a localized, reciprocal interaction between breast cancer cells and the surrounding mammary white adipose tissue. To investigate how breast cancer cells alter the composition and function of adipose tissue, we screened the secretomes of ten human breast cancer cell lines for the ability to modulate the differentiation of adipocyte s...

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Literature Corpus work: 9ca88e3d-d93e-5981-88c7-15330f62ec2d
DOI: 10.1101/2024.03.04.583349

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