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Genome graphs reveal the importance of structural variation in <i>Mycobacterium tuberculosis</i> evolution and drug resistance

2025-05-07

Abstract excerpt

Structural variants (SVs) are increasingly recognized as key drivers of bacterial evolution, yet their role has not been explored thoroughly. This is due to limitations in traditional short-read sequencing and linear reference-based analyses, which can miss complex structural changes. Tuberculosis (TB), a disease caused by Mycobacterium tuberculosis ( Mtb ), remains a major global health concern. In this study,...

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Literature Corpus work
dcea40c2-81ee-5bf8-a965-3cbec1d65447
DOI
10.1101/2025.05.07.652570
Open publication

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Genome graphs reveal the importance of structural variation in <i>Mycobacterium tuberculosis</i> evolution and drug resistanceDOI 10.1101/2025.05.07.652570
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