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Article

Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome of epidemic strains in China.

PloS one - 1 Jan 2025

Zhou Yang, Anthony Richard, Wang Shengfen, Xia Hui, Ou Xichao, Zhao Bing, Song Yuanyuan, Zheng Yang, He Ping, Liu Dongxin, Zhao Yanlin, van Soolingen Dick

Abstract excerpt

Tuberculosis is a major public health threat resulting in more than one million lives lost every year. Many challenges exist to defeat this deadly infectious disease which address the importance of a thorough understanding of the biology of the causative agent Mycobacterium tuberculosis (MTB). We generated a non-redundant pangenome of 420 epidemic MTB strains from China including 344 Lineage 2 strains, 69 Lineage...

Read the complete abstract on PubMed

Topics

Mycobacterium tuberculosis
China
Humans
Tuberculosis
Genome, Bacterial
Epidemics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Evolution, Molecular

Phylogeny

Genetic Variation

Source

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Identifiers

PMID: 40388514
DOI: 10.1371/journal.pone.0324152
PMCID: PMC12143926

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