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The MAGMA pipeline for comprehensive genomic analyses of clinical Mycobacterium tuberculosis samples

29 Nov 2023

Abstract excerpt

BACKGROUND: Whole genome sequencing (WGS) holds great potential for the management and control of tuberculosis. Accurate analysis of samples with low mycobacterial burden, which are characterized by low (<20x) coverage and high (>40%) levels of contamination, is challenging. We created the MAGMA (Maximum Accessible Genome for Mtb Analysis) bioinformatics pipeline for analysis of clinical Mtb samples. METHODS AND...

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PMID: 38019772
DOI: 10.1371/journal.pcbi.1011648

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