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Defining the <i>Mycobacterium tuberculosis</i> Pangenome and Suggestions for a New Composite Reference Sequence

2025-11-03

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb) causes tuberculosis (TB), a global disease with diverse clinical and microbiological manifestations. Studies into the biological causes of this phenotypic diversity have been largely limited to a few reference strains. A pangenome approach is likely to provide new insights. Pangenomic tuberculosis studies have been limited the availability of only fragmented geno...

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Literature Corpus work
7309ca01-625a-5ebc-9115-e46bc57c4437
DOI
10.1101/2025.11.03.686283
Open publication

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