Article

Mutational analysis of N-ethyl-N-nitrosourea (ENU) in the fission yeast Schizosaccharomyces pombe.

2018-12-03

Abstract excerpt

Forward genetics has boosted our knowledge on genic function in a multitude of biological models and it has significantly contributed to the understanding of genetic bases of development, ageing and human diseases. With the advent of the next generation sequencing and use of powerful bioinformatic tools, this traditional genetic strategy has acquired a new impulse. At present, whole genome sequencing assisted by i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dce5aa12-fc7d-59c3-a63b-c218308e1c80
DOI: 10.1101/486266

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of N-ethyl-N-nitrosourea (ENU) in the fission yeast Schizosaccharomyces pombe.DOI 10.1101/486266Read

Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe.Semantic proximity Read

Evaluation of the genetic alterations induced by chemical mutagens in Schizosaccharomyces pombe.Semantic proximity Read

Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.Semantic proximity Read

ENU-induced phenovariance in mice: inferences from 587 mutations.Semantic proximity Read

Further characterisation of processes removing EMS premutational lesions in yeast (S. cerevisiae).Semantic proximity Read

Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.Semantic proximity Read

Whole-genome profiling of mutagenesis in Caenorhabditis elegans.Semantic proximity Read

Analysis of multiple ethyl methanesulfonate-mutagenized Caenorhabditis elegans strains by whole-genome sequencing.Semantic proximity Read

Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.Semantic proximity Read

A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage.Semantic proximity Read

N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3' Splice Site Function in Vivo.Semantic proximity Read

Whole-genome high-fidelity sequencing: A novel approach to detecting and characterization of mutagenicity in vivo.Semantic proximity Read