Article
Parallel Structural Evolution of Mitochondrial Ribosomes and OXPHOS Complexes.
Genome biology and evolution - 9 Apr 2015
van der Sluis Eli O, Bauerschmitt Heike, Becker Thomas, Mielke Thorsten, Frauenfeld Jens, Berninghausen Otto, Neupert Walter, Herrmann Johannes M, Beckmann Roland
Abstract excerpt
The five macromolecular complexes that jointly mediate oxidative phosphorylation (OXPHOS) in mitochondria consist of many more subunits than those of bacteria, yet, it remains unclear by which evolutionary mechanism(s) these novel subunits were recruited. Even less well understood is the structural evolution of mitochondrial ribosomes (mitoribosomes): while it was long thought that their exceptionally high...
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