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Article

Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome.

Science (New York, N.Y.) - 17 Apr 2015

Greber Basil J, Bieri Philipp, Leibundgut Marc, Leitner Alexander, Aebersold Ruedi, Boehringer Daniel, Ban Nenad

Abstract excerpt

Mammalian mitochondrial ribosomes (mitoribosomes) synthesize mitochondrially encoded membrane proteins that are critical for mitochondrial function. Here we present the complete atomic structure of the porcine 55S mitoribosome at 3.8 angstrom resolution by cryo-electron microscopy and chemical cross-linking/mass spectrometry. The structure of the 28S subunit in the complex was resolved at 3.6 angstrom resolution...

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Identifiers

PMID: 25837512
DOI: 10.1126/science.aaa3872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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