Article

MAFB surrogates the glucocorticoid receptor ability to induce tolerogenesis in dendritic cells

2021-07-28

Abstract excerpt

Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the glucocorticoid receptor (GR). Dendritic cells (DCs), central actors for coordinating immune responses, acquire tolerogenic properties in response to GCs. Tolerogenic DCs (tolDCs) have emerged as a potential treatment for various inflammatory diseases. To date, the underlying cell type-specific regulatory mechanisms orchestrati...

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Literature Corpus work: dc756a1b-ab7c-56b7-bb36-277758ba9ba3
DOI: 10.1101/2021.07.27.453975

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