Article

Vitamin C triggers NF-κB-driven epigenomic reprogramming and enhanced immunogenic responses of dendritic cells

2022-05-29

Abstract excerpt

<h4>ABSTRACT</h4> Dendritic cells (DCs) are central in the immune system, bridging the adaptive and innate immune responses. Research on in vitro differentiation of DCs from monocytes provides both in-depth understanding of the analogous in vivo process and potential sources for cancer cell therapy. Active DNA demethylation is crucial in DC differentiation. Vitamin C is a known cofactor of ten-eleven translocati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25eb9304-f0ed-5376-9943-0073d23450c6
DOI: 10.1101/2022.05.26.493381

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Vitamin C triggers NF-κB-driven epigenomic reprogramming and enhanced immunogenic responses of dendritic cellsDOI 10.1101/2022.05.26.493381Read

Epigenetic signature of human vitamin D3 and IL-10-conditioned regulatory DCsSemantic proximity Read

Vitamin D Signaling in the Context of Innate Immunity: Focus on Human MonocytesSemantic proximity Read

Increased phenotypic and functional stability of human allospecific induced Tregs is associated with Vitamin C-mediated FOXP3 TSDR demethylation.Semantic proximity Read

Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 via methyl-dependent changes in epigenetic marksSemantic proximity Read

An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19Semantic proximity Read

Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 via methyl-dependent changes in epigenetic markingsSemantic proximity Read

Primary Vitamin D Target Genes of Human MonocytesSemantic proximity Read

Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia.Semantic proximity Read

Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseasesSemantic proximity Read

Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1Semantic proximity Read

Modulating Epigenetic Memory through Vitamins and TET: Implications for Regenerative Medicine and Cancer TreatmentSemantic proximity Read

A Review: Highlighting the Links between Epigenetics, COVID-19 Infection, and Vitamin DSemantic proximity Read