Article

Protein-coding and rRNA variants drive a mitochondrial DNA genotype that associates to low birth weight and is more common in individuals born after assisted reproductive technologies

2023-01-09

Abstract excerpt

<title>Abstract</title> <p>Children born using assisted reproductive technologies (ART) have an increased risk of a lower birth weight, the cause of which remains unclear. As a causative factor, we hypothesized that variants in the mitochondrial DNA (mtDNA) that are not associated with disease, may explain changes in birth weight. We deep-sequenced the mtDNA of 451 ART and spontaneously conceived (SC) individuals...

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Literature Corpus work: dc57f125-822a-5118-b09b-5a7a09b9aeeb
DOI: 10.21203/rs.3.rs-2337956/v1

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