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Effects of adverse fertility-related factors on mitochondrial DNA in the oocyte: a comprehensive review

17 Mar 2023

Abstract excerpt

The decline of oocyte quality has profound impacts on fertilization, implantation, embryonic development, and the genetic quality of future generations. One factor that is often ignored but is involved in the decline of oocyte quality is mitochondrial DNA (mtDNA) abnormalities. Abnormalities in mtDNA affect the energy production of mitochondria, the dynamic balance of the mitochondrial network, and the...

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PMID: 36932444
DOI: 10.1186/s12958-023-01078-6

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