Article
Differences in maternally inherited and age-related de novo mitochondrial DNA variants between ART and spontaneously conceived individuals associate with low birth weight
2022-09-06
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background</h4> Children born using assisted reproductive technologies (ART) have an increased risk of a lower birth weight, the cause of which remains unclear. As a causative factor, we hypothesized that variants in the mitochondrial DNA (mtDNA) that are not associated with disease, may explain changes in birth weight. <h4>Methods</h4> We deep-sequenced the mtDNA of 451 ART and spontaneously...
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Identifiers and source
- Literature Corpus work
- eae851ed-04e5-5e4e-94f4-de60fcb5afd7
- DOI
- 10.1101/2022.09.05.22279608
