Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleotide variations in mitochondrial DNA and supra-physiological ROS levels in cytogenetically normal cases of premature ovarian insufficiency.

Archives of gynecology and obstetrics - 1 Dec 2010

Kumar Manoj, Pathak Dhananjay, Kriplani Alka, Ammini A C, Talwar Pankaj, Dada Rima

Abstract excerpt

Premature ovarian insufficiency (POI) is defined as the cessation of ovarian function under the age of 40 years and is characterized by amenorrhea, hypoestrogenism, and elevated serum gonadotrophin concentration (FSH). It is a heterogeneous disorder with a multicausal pathogenesis; however, majority of cases are idiopathic. In idiopathic POI, involvement of unknown mechanisms may increase rate of oocyte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Mitochondrial

Share to Oxidative Stress

Share to Polymorphism, Single Nucleotide

Share to Primary Ovarian Insufficiency

Share to Reactive Oxygen Species

Source

Identifiers

PMID: 20680310
DOI: 10.1007/s00404-010-1623-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleotide variations in mitochondrial DNA and supra-physiological ROS levels in cytogenetically normal cases of premature ovarian insufficiency.PMID 20680310Read ↗

Oxidative stress and ATPase6 mutation is associated with primary ovarian insufficiency.Semantic proximity Read ↗

Increased Incidence of Mitochondrial Cytochrome C Oxidase 1 Gene Mutations in Patients with Primary Ovarian Insufficiency.Semantic proximity Read ↗

Mitochondrial Dysfunction in Primary Ovarian InsufficiencySemantic proximity Read ↗

Role of reactive oxygen species in the pathogenesis of mitochondrial DNA (mtDNA) mutations in male infertility.Semantic proximity Read ↗

Whole-exome sequencing reveals new potential genes and variants in patients with premature ovarian insufficiency.Semantic proximity Read ↗

Oxidative stress and sperm mitochondrial DNA mutation in idiopathic oligoasthenozoospermic men.Semantic proximity Read ↗

The Role of Mitochondria in Human Fertility and Early Embryo Development: What Can We Learn for Clinical Application of Assessing and Improving Mitochondrial DNA?Semantic proximity Read ↗

A Comprehensive Review of the Contribution of Mitochondrial DNA Mutations and Dysfunction in Polycystic Ovary Syndrome, Supported by Secondary Database AnalysisSemantic proximity Read ↗

Mitochondrial DNA disorders: from pathogenic variants to preventing transmission.Semantic proximity Read ↗

Genetic insights into the complexity of premature ovarian insufficiency.Semantic proximity Read ↗

Blood Cell Mitochondrial DNA Content and Premature Ovarian AgingSemantic proximity Read ↗

DNA double-strand break genetic variants in patients with premature ovarian insufficiencySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.