Article
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against <i>Streptococcus pneumoniae</i>
2022-01-21
Abstract excerpt
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and an important cause of childhood mortality. Despite the introduction of successful vaccines, the global spread of both non-vaccine serotypes and antibiotic-resistant strains reinforce the development of alternative therapies against this pathogen. One possible route is the development of monoclonal antibodies (mAbs) that induce killin...
Topics
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- Bacterial Infections and Vaccines
- Carbohydrate Chemistry and Synthesis
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Toxin Mechanisms and Immunotoxins
Identifiers and source
- Literature Corpus work
- dc2cf38b-cd1a-5f4e-a09b-a20d44cb2a2d
- DOI
- 10.1101/2022.01.21.477211
