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Streptococcus pneumoniae Capsular Polysaccharide

12 Apr 2019

Abstract excerpt

is the dominant surface structure of the organism and plays a critical role in virulence, principally by interfering with host opsonophagocytic clearance mechanisms. The capsule is the target of current pneumococcal vaccines, but there are 98 currently recognised polysaccharide serotypes and protection is strictly serotype-specific. Widespread use of these vaccines is driving changes in serotype prevalence in...

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PMID: 30977464
DOI: 10.1128/microbiolspec.gpp3-0019-2018

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