Article

Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency

2024-11-07

Abstract excerpt

<title>Abstract</title> <p>Reprogramming somatic cells into human induced pluripotent stem cells entails profound intracellular changes, including modifications in mitochondrial metabolism and a decrease in the mitochondrial DNA copy number. However, the mechanisms underlying this decline in mitochondrial DNA copy number during reprogramming remain unclear. In this study, we aimed to elucidate these underlying me...

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Literature Corpus work: dc1f898e-2f45-5cfa-a950-71c16f7c669e
DOI: 10.21203/rs.3.rs-5148938/v1

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