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Genetic associations with human longevity are enriched for oncogenic genes

2024-08-01

Abstract excerpt

Human lifespan is shaped by both genetic and environmental exposures and their interaction. To enable precision health, it is essential to understand how genetic variants contribute to earlier death or prolonged survival. In this study, we tested the association of common genetic variants and the burden of rare non-synonymous variants in a survival analysis, using age-at-death (N = 35,551, median [min, max] = 72.4...

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Literature Corpus work
dbf72d3e-9945-5ba6-9e5e-d0fd5a84c434
DOI
10.1101/2024.07.30.24311226
Open publication

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Genetic associations with human longevity are enriched for oncogenic genesDOI 10.1101/2024.07.30.24311226
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