Article
Unique Combinations of epigenetic modifiers synergistically impair the viability of the U87 glioblastoma cell line while exhibiting minor or moderate effects on normal stem cell growth
2021-11-23
Abstract excerpt
<title>Abstract</title> <p>Discoveries made over the last decade have shown that critical changes in cancer cells, such as activation of oncogenes and silencing of tumor suppressor genes are caused not only by genetic but also by epigenetic mechanisms. While epigenetic alterations are somatically heritable, in contrast to genetic changes, they are potentially reversible, making them perfect targets for therapeuti...
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Identifiers and source
- Literature Corpus work
- dbe6bba8-35cf-5101-ac7a-aa21e2a70150
- DOI
- 10.21203/rs.3.rs-1072015/v1
