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Unique Combinations of epigenetic modifiers synergistically impair the viability of the U87 glioblastoma cell line while exhibiting minor or moderate effects on normal stem cell growth

2021-11-23

Abstract excerpt

<title>Abstract</title> <p>Discoveries made over the last decade have shown that critical changes in cancer cells, such as activation of oncogenes and silencing of tumor suppressor genes are caused not only by genetic but also by epigenetic mechanisms. While epigenetic alterations are somatically heritable, in contrast to genetic changes, they are potentially reversible, making them perfect targets for therapeuti...

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Literature Corpus work
dbe6bba8-35cf-5101-ac7a-aa21e2a70150
DOI
10.21203/rs.3.rs-1072015/v1
Open publication

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Unique Combinations of epigenetic modifiers synergistically impair the viability of the U87 glioblastoma cell line while exhibiting minor or moderate effects on normal stem cell growthDOI 10.21203/rs.3.rs-1072015/v1
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