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RNA polymerase III transcription-associated polyadenylation promotes the accumulation of noncoding retrotransposons during infection

2025-05-16

Abstract excerpt

<h4>ABSTRACT</h4> The accumulation of RNA Polymerase III (Pol III) transcribed short interspersed nuclear element (SINE) retrotransposon RNA is a hallmark of various cellular stressors, including DNA virus infection. However, the molecular mechanisms driving the induction of these normally repressed loci are largely undefined. Here, we reveal that in addition to Pol III transcriptional induction, gammaherpesvirus...

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Literature Corpus work
dbd720a7-53c0-5270-9cbe-ab54c309b505
DOI
10.1101/2025.05.14.654096
Open publication

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RNA polymerase III transcription-associated polyadenylation promotes the accumulation of noncoding retrotransposons during infectionDOI 10.1101/2025.05.14.654096
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