Article

Di-arginine and FFAT-like motifs retain a subpopulation of PRA1 at ER-mitochondria membrane contact sites

2020-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Prenylated Rab Acceptor 1 (PRA1/Rabac1) is a four-pass transmembrane protein that has been found to localize to the Golgi and promiscuously associate with a diverse array of Rab GTPases. We have previously identified PRA1 to be among the earliest significantly down-regulated genes in the rd1 mouse model of retinitis pigmentosa, a retinal degenerative disease. Here, we show that an endogenous su...

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Literature Corpus work: dbb704f6-be82-5f2a-9893-3ff4857a07d0
DOI: 10.1101/2020.01.27.922260

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