Article

Rare event of NTRK3 rearrangement and amplification in esophageal squamous cell carcinoma

2022-03-23

Abstract excerpt

<h4>Background: </h4> TRK tyrosine kinase inhibitors (larotrectinib or entrectinib) can cause an unknown histological response in NTRK fusion-positive cancer patients,and it has been approved by the US Food and Drug Administration.The neurotrophic tyrosine kinase receptor (NTRK) 3 gene rearrangements is a target of tyrosine kinase inhibitors.We attempted to assess the correlation of NTRK3 gene rearrangement and ge...

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Literature Corpus work: db731fa2-0809-54c3-bfcb-a01f8bcad522
DOI: 10.21203/rs.3.rs-1387968/v2

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