Article

Mapping of m <sup>6</sup> A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance

2021-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Recent evidence has highlighted the role of N 6 -methyladenosine (m 6 A) in the regulation of mRNA expression, stability and translation, supporting a potential role for post-transcriptional regulation mediated by m 6 A in cancer. Here we explore prostate cancer as an exemplar and demonstrate that low levels of N 6 -adenosine-methyltransferase ( METTL3 ) is associated with advanced metastat...

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Literature Corpus work: db254e4f-08c0-5617-ad17-a5668420a224
DOI: 10.1101/2021.01.12.426354

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Mapping of m <sup>6</sup> A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy ResistanceDOI 10.1101/2021.01.12.426354Read

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