Article

Prognostic Value and Possible Mechanism of m6A Methyltransferase METTL3 in Prostate Cancer

2022-01-17

Abstract excerpt

<h4>Background: </h4> The N6-methyladenosine (m6A) methyltransferase METTL3 has been reported to be closely related to prostate cancer (PCa). Thus, we aimed to explore its prognostic value and possible mechanism in PCa. <h4>Methods: </h4>: The METTL3 gene and protein expression status in between the PCa and normal tissues as well as the correlation between METTL3 and Gleason score (GS) were evaluated using The Can...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cd88aa42-83c8-54e8-8a07-10fbcc66a622
DOI: 10.21203/rs.3.rs-1204194/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prognostic Value and Possible Mechanism of m6A Methyltransferase METTL3 in Prostate CancerDOI 10.21203/rs.3.rs-1204194/v1Read

Construction of risk prediction model using m6A RNA methylation regulators in prostate cancer: comprehensive bioinformatic analysis and histological validationSemantic proximity Read

An N6-methyladenosine-Related Classification Predicts Prognosis and Response to Immunotherapy in Prostate cancerSemantic proximity Read

Subtypes of m6A RNA Modification Defines Tumor Microenvironment, Immunotherapy and Pharmacogenomic Landscape in Prostate CancerSemantic proximity Read

m6A Methylation Regulators Are Predictive Biomarkers for Tumour Metastasis in Prostate CancerSemantic proximity Read

Integrative analyses of DNA methylase expression and related immune landscape in Prostate CancerSemantic proximity Read

METTL3 drives malignant progression in TP53-mutant prostate cancer.Semantic proximity Read

Bioinformatic determination of the expression and clinical value of the histone lysine demethylase family in prostate cancerSemantic proximity Read

Prediction of Prognosis in Patients with Prostate Cancer by DNA Methylation ClassificationSemantic proximity Read

Molecular Characterization and Clinical Relevance of m6A Regulators in Metastatic Prostate CancerSemantic proximity Read

The Prognosis-Predictive and Immunoregulatory Role of SUMOylation Related Genes: Potential Novel Targets in Prostate Cancer TreatmentSemantic proximity Read

Establishment of a 5 DNA Methylation Site Prognostic Signature Associated with N6-Methyladenosine in Lung AdenocarcinomaSemantic proximity Read

A N7-Methylguanine-Related Gene Signature Applicable for the Prognosis and Microenvironment of Prostate CancerSemantic proximity Read