Article
DNA microarray analysis reveals metastasis-associated genes in rat prostate cancer cell lines.
Biomedica : revista del Instituto Nacional de Salud - 1 Jun 2007
Reyes Ismail, Tiwari Raj, Geliebter Jan, Reyes Niradiz
Abstract excerpt
INTRODUCTION: The molecular and cellular mechanisms involved in prostate cancer progression towards a hormone-independent and highly invasive, metastatic phenotype, are not well understood. Cell lines with different metastatic potential, when analyzed by microarray techniques, offer valuable tools for identifying genes associated with the metastatic phenotype. OBJECTIVES: Gene expression profiles were compared...
Topics
- Animals
- Biomarkers
- Cell Line, Tumor
- Gene Expression Profiling
- Humans
- Male
- Molecular Sequence Data
- Neoplasm Metastasis
- Oligonucleotide Array Sequence Analysis
- Phenotype
- Prostatic Neoplasms
- Rats
