Article

RIG-I Stimulation Enhances Effector Function and Proliferation of Primary Human CD8 T Cells

2025-01-29

Abstract excerpt

Cytotoxic CD8 T lymphocytes (CTL) are crucial in antiviral immune responses. However, their recruitment to infection sites renders them at risk of viral infection that could modulate their effector activity. CTL express RIG-I that detects cytosolic viral RNA and subsequently induce antiviral gene expression. Here, we investigated how influenza A virus (IAV) infection influence TCR-dependent effector responses. IAV...

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Literature Corpus work: daceed4e-033e-5fce-978d-d3808c8eb2e4
DOI: 10.1101/2025.01.27.635030

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