Article

Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an <i>in vitro</i> model of the osteoarthritis phenotype

2020-06-18

Abstract excerpt

<h4>Summary</h4> <h4>Objective</h4> Fibronectin is a matrix protein that is fragmented during cartilage degradation in osteoarthritis (OA). Treatment of chondrocytes with fibronectin fragments (FN-f) has been used to model OA in vitro , but the system has not been fully characterized. This study sought to define the transcriptional response of chondrocytes to FN-f, and directly compare it to responses tradition...

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Literature Corpus work: dac7e877-8354-5abb-ab7d-ad9d9cc5277c
DOI: 10.1101/2020.06.18.155390

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