Article

Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

2016-01-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Osteoarthritis (OA) is a common disease characterized by cartilage degeneration and joint remodeling. The underlying molecular changes underpinning disease progression are incompletely understood, but can be characterized using recent advances in genomics technologies, as the relevant tissue is readily accessible at joint replacement surgery. Here we investigate genes and pa...

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Literature Corpus work: 04158199-03b8-5c66-b461-426993e88e78
DOI: 10.1101/038067

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