Article

EZH2 Alleviates Antituberculosis Drug-Induced Liver Injury in Mice by Reducing H3K27 Trimethylation at the Nrf2 Promoter

2021-07-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Anti-tuberculosis drug-induced liver injury (ADLI) limits the treatment of tuberculosis. The mechanisms underlying ADLI are unclear and there are no effective preventative measures to avoid this complication. <bold>Methods</bold>In this stuy, the protein contents of EZH2, Nrf2, NQO1 and HO-1 were detected by ELISA kit, while those of EZH2 and Nrf2 were determined...

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Literature Corpus work: 35998f92-7e6f-5b51-8cf9-71855fc215f7
DOI: 10.21203/rs.3.rs-701850/v1

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