Article

Astrocytic lactoferrin deficiency augments MPTP-induced dopaminergic neuron loss by disturbing ER-mitochondria signaling

2022-04-26

Abstract excerpt

<title>Abstract</title> <p>Increased levels of lactoferrin (Lf) are present in the aged brain and in the lesions of various neurodegenerative diseases, including Parkinson’s disease (PD), may contribute to the cascade of events involved in neurodevelopment and neuroprotection. However, whether Lf originates from astrocytes and functions within either the normal or pathological brain are unknown. Here, we employed...

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Literature Corpus work: da4ca56f-307e-5db4-be76-b886b401e32d
DOI: 10.21203/rs.3.rs-1558216/v1

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