Article

Microhomology-mediated end-joining Knock-In approaches to delete the allergenic domain of trout parvalbumin beta-1. Preliminary results in F0 animals and feedback

2025-02-25

Abstract excerpt

<h4>Background: </h4> Gene editing techniques offer new opportunities to improve important traits in aquaculture. The allergenicity of fish flesh is a major problem in aquaculture. Parvalbumin (Parv) is the most prevalent fish allergen. For instance, in salmonids, a single parvalbumin beta-1 protein (parvb1) has been identified as an allergen in specific patients. Therefore, generating trout carrying two parvb1 al...

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Literature Corpus work: da315c5c-4712-5699-96a9-7e3be8cc269b
DOI: 10.12688/openreseurope.18223.2

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