Article

Genetically predicted levels of the human plasma proteome and risk of stroke: a Mendelian Randomization study

2021-11-15

Abstract excerpt

<title>Abstract</title> <p>Proteins are the effector molecules of biology and are the target of most drugs. To identify proteins and related pathways that may play a causal role in stroke pathogenesis, we used Mendelian randomisation (MR). We tested potential causal effects of 308 plasma proteins (measured in 4,994 blood donors from the INTERVAL study) on stroke outcomes (derived from the MEGASTROKE GWAS) in a tw...

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Literature Corpus work: da1f34f8-f6c3-579e-a7a5-9698d913520d
DOI: 10.21203/rs.3.rs-984362/v1

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