Article

A new method to accurately identify single nucleotide variants using small FFPE breast samples

2020-10-23

Abstract excerpt

Most tissue collections of neoplasms are composed of formalin-fixed and paraffin-embedded (FFPE) excised tumor samples used for routine diagnostics. DNA sequencing is becoming increasingly important in cancer research and clinical management; however, it is difficult to accurately sequence DNA from FFPE samples. We developed and validated a new bioinformatic algorithm to robustly identify somatic single nucleotide...

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Literature Corpus work: d9e69afe-d907-5a8c-aa09-01fdf6d2783c
DOI: 10.1101/2020.10.22.350983

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